SCS-C001294

streptochlorin

Pathway: Alkaloids

Chemical Structure

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Source Information

Streptomyces fradiae CH06 (NA)

Kingdom Bacillati Phylum Actinomycetota Class Actinomycetes Order Kitasatosporales Family Streptomycetaceae Genus Streptomyces Species Streptomyces fradiae

South China Sea

DOI: 10.1016/j.pestbp.2025.106675 · Pesticide Biochemistry and Physiology

Drug-likeness (Lipinski Ro5)

Molecular Weight

218.6 Da

Threshold ≤ 500

ALogP

3.48

Threshold ≤ 5

H-Bond Donors

Threshold ≤ 5

H-Bond Acceptors

Threshold ≤ 10

Passes Lipinski Rule of Five — drug-like candidate

Chemical Properties

Molecular Formula:

C11H7ClN2O

Molecular Weight:

218.6400 Da

SMILES:

Clc1ncoc1-c1c[nH]c2ccccc12

InChIKey:

                        BKYJGKRXUHPPLR-UHFFFAOYSA-N
                        
                    

InChI:

InChI=1S/C11H7ClN2O/c12-11-10(15-6-14-11)8-5-13-9-4-2-1-3-7(8)9/h1-6,13H

Calculated Properties

ALogP:

3.476 lipophilicity

TPSA:

41.82 Å² polar surface area

H-Bond Donors:

H-Bond Acceptors:

Rotatable Bonds:

Ring Count:

3 (3 aromatic)

Chiral Centers:

Fsp³:

0.0000 fraction sp³ carbon

Database Information

Compound ID:

SCS-C001294

NPClassifier Pathway:

Alkaloids

NPClassifier Superclass:

N/A

NPClassifier Class:

N/A

Glycoside:

NPClassifier Status:

Classified

External Links:

General chemistry

PubChem ChemSpider ChEMBL

Natural product databases

COCONUT NP Atlas

Biological Activity Data

Activity values are displayed only when a quantitative or clearly reported result is available. Tested organisms, cell lines and molecular targets are shown under Target / model.

Activity	Assay	Target / model	Result	Reference
Antifungal	EC50	Fusarium oxysporum f. sp. cubense Race4	7.0 μg/mL	10.1016/j.pestbp.2025.106675 Pesticide Biochemistry and Physiology
Antifungal	inhibition_percent	10 phytopathogens (Botrytis cinerea, Colletotrichum capsica, etc.)	> 70.0 %	10.1016/j.pestbp.2025.106675 Pesticide Biochemistry and Physiology
Antifungal	EC50	GPI-anchored protein biosynthesis pathway	95.5 %	10.1016/j.pestbp.2025.106675 Pesticide Biochemistry and Physiology

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